A timely and helpful guide and infographic was published by the Pharmaceutical Journal on 25th July. It aims to tell pharmacists what they need to know. It includes a distinction between THC and CBD, important to know when talking about cannabis, its legalisation and derivatives. THC is the psychoactive component of cannabis. Weak partial agonist on CB1 and CB2 receptors. THC potency in dried cannabis has increased from an average of 3% in the 1980s to around 15% today. Some strains contain more than 25% potency. CBD (cannabidiol) does not produce psychoactive adverse effects. Has little affinity for CB1 and CB2 receptors directly. It is believed to modulate the effects of THC throughout the endocannabinoid system which is why the THC/CBD ratio can lead to different responses and adverse effects. It also details where cannabis is legal, illegal or decriminalised.
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